Pemberian infusa teh hijau (Camellia sinensis) terhadap struktur histologis paru yang dipapar asap rokok kretek pada mencit (Mus Muscullus)

Ayuningtias, Apriska (2020) Pemberian infusa teh hijau (Camellia sinensis) terhadap struktur histologis paru yang dipapar asap rokok kretek pada mencit (Mus Muscullus). Bachelor (S1) thesis, Wijaya Kusuma Surabaya University.

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Abstract

This study was conducted to analyze the effect of antioxidant administration from green tea infusion (Camellia sinensis) on damage to the histological structure of the lung exposed to clove cigarette smoke in mice (Mus muscullus). Free radicals in cigarette smoke such as tar, nicotine, and carbon monoxide can cause various damages to the lung organs due to oxidative stress caused by the reaction of ultrafine particles with cells. A total of 27 mice were taken from the Biochemical Laboratoryn of Airlangga University, Surabaya. In this study mice (Mus muscullus) were exposed to kretek cigarette smoke in the smoking chamber for 15 minutes in a period of 2 weeks, used 2 variants of antioxidant doses of green tea infusion of 0.45 gr to 0.6 gr. After the treatment was completed, the preparation of the mice's pulmonary organ preparations and damage to the structure of the lung organ were observed in 5 visual fields. The results showed that there was a relationship between the amount of cigarette smoke exposed and damage to the lung organs of mice when given antioxidant green tea. The administration of green tea antioxidants reduced inflammation of the lung organ infiltration of inflammatory cells by 44%, edema by 55%, and destruction of septa alveoli by 88%. From this study it can be concluded that green tea has an antioxidant effect that can improve the histological structure of the lungs exposed to kretek cigarette smoke in mice

Item Type:	Thesis (Bachelor (S1))
Uncontrolled Keywords:	Green tea (Camellia sinensis), mice (Mus muscullus), cell infiltration, edema, destruction
Subjects:	R Medicine > RB Pathology
Divisions:	Faculty of Vetenary Medicine > Vetenary Education Study Program
Depositing User:	Apriska Ayuningtias UWKS
Date Deposited:	10 Sep 2020 06:46
Last Modified:	10 Sep 2020 06:46
URI:	http://erepository.uwks.ac.id/id/eprint/7019

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