Pengaruh Pemberian Ekstrak Peperomia Pellucida Terhadap Penurunan Ekspresi Transforming Growth Factor-ß Pada Ginjal Tikus Wistar Jantan Yang Di Induksi Pajanan Asap Rokok

Anggono, Susan Jocelyn (2024) Pengaruh Pemberian Ekstrak Peperomia Pellucida Terhadap Penurunan Ekspresi Transforming Growth Factor-ß Pada Ginjal Tikus Wistar Jantan Yang Di Induksi Pajanan Asap Rokok. [Tugas Akhir/Skripsi] (Unpublished)

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Abstract

Peperomia Pellucida extract can effect the reduction of Transforming Growth Factor – ß expression in the renal of male wistar rat that being exposed with cigarette smoke. Method : True experimental, post test only control group design, simple random Result Conclusion KeyWords sampling. Sample: 21 male wistar rat 8 - 12 weeks with 180-200 gr of weight. This research divided to 3 groups. These groups are again divided to 1 control group and 2 treatment groups. The control group (K0) was fed with standard meals for 5 weeks then, the first treatment group (P1) were fed with standard meals for 1 week and exposed with cigarette smoke for 4 weeks (1 cigarette /1 rat/ day) with the same standard meals. The second (P2) treatment group were fed with standard meals and given with Peperomia Pellucida extract (400mg/kg/body weight from a nasogastric tube) for 1 week and being exposed to cigarette smoke for 4 weeks (1 cigarette /1 rat/ day) and fed with standard meals and Peperomia Pellucida extract (400mg/kg/body weight from a nasogastric tube). The research’s data result was proceed with statistic computer program (SPSS 27.0) with one way annova test. : The result of this research shows a significant effect of the Transforming Growth Factor-ß expression to the renal of male wistar rat that being exposed with cigarette smoke. : The given Peperomia pellucida extract can reduce Transforming Growth Factor-ß expression in the renal of male wistar rat that being exposed with cigarette smoke. : Cigarette smoke, Male wistar rat, Peperomia Pellucida extract, Transforming Growth Factor-ß.

Item Type:	Tugas Akhir/Skripsi
Uncontrolled Keywords:	Cigarette smoke, Male wistar rat, Peperomia Pellucida extract, Transforming Growth Factor-ß.
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine > Medical Doctor Profession Education Study Program
Depositing User:	Susan Jocelyn Anggono
Date Deposited:	11 Apr 2025 05:43
Last Modified:	11 Apr 2025 05:43
URI:	http://erepository.uwks.ac.id/id/eprint/19879

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