Mixed Mammary Carcinosarcoma in Domesticated Asian Palm Civet (Paradoxurus hermaphroditus)

Widyawati, Ratna (2019) Mixed Mammary Carcinosarcoma in Domesticated Asian Palm Civet (Paradoxurus hermaphroditus). World’s Veterinary Journal. (Unpublished)

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Abstract

A female Asian palm civet (Paradoxurus hermaphroditus), three years old was carried for a medical checkup to Ruddy animal's clinic in Sidoarjo, East Java, Indonesia. The civet suffers enlargement of abdominal mammary glands, painless lump, asymmetric size (4.1 and 8.4 cm in diameter), and lacerated wound on the large one with severe haemorrhage. The unilateral mastectomy was conducted under anaesthesia to handles both haemorrhage and tumour mass. Following the surgery, the tumour mass was stored in 10% neutral buffer formalin for histopathology using Hematoxylin & Eosin (H&E) staining and immunohistochemistry against antibody, anti-CD4+ and CD8+, further, a blood sample collected before and after surgery (on days: 0, 7, 30, and 60) for representing the healing progress. The chemotherapy was given using the combination of oral cyclophosphamide and intravenous injection of vincristine. According to laboratory results, the final diagnosis was mixed mammary carcinosarcoma with minimal expression of CD8+, notwithstanding, it showed the better prognosis after surgery and chemotherapy. Key words: Asian palm civet, CD4+, CD8+, Mixed mammary carcinosarcoma, Therapy

Item Type:	Other
Subjects:	S Agriculture > SF Animal culture
Divisions:	Faculty of Vetenary Medicine > Animal Health and Veteriner Public Health Study Program
Depositing User:	Sulimin BP3
Date Deposited:	09 Aug 2023 02:14
Last Modified:	09 Aug 2023 02:14
URI:	http://erepository.uwks.ac.id/id/eprint/15109

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