Perbandingan Aktivitas Linimentum Ekstrak Koral Kelimutu dan Linimentum Ekstrak Daun Lamtoro (Leucaena leucochepala) Terhadap Penyembuhan Scabies Pada Kelinci (Oryctolagus cuniculus)

Rahayu, Asih (2015) Perbandingan Aktivitas Linimentum Ekstrak Koral Kelimutu dan Linimentum Ekstrak Daun Lamtoro (Leucaena leucochepala) Terhadap Penyembuhan Scabies Pada Kelinci (Oryctolagus cuniculus). Univ.Gadjah Mada Yogyakarta. (Unpublished)

Text 6. Perbandingan Aktivitas Linimentum Ekstrak Koral Kelimutu dan.pdf Download (648kB)

Abstract

Abstract The purpose of this study was to compare the activity of liniment of coral kelimutu extract and lamtoro leaf extract (Leucaena leucochepala) as a scabies healing therapy in rabbits (Oryctolagus cuniculus). This type of experimental research was using Completely Randomized Design (CRD).Animal samples were 24 male rabbits aged 4-6 weeks that divided into four groups, namely the negative control / normal , untreated (P0), positive control: treated liniment sulfur ppt (P1), treated liniment lamtoro leaf extract (P2), and treated liniment coral kelimutu extract (P3). All rabbit fur were shaved in the anterior dorsal area about 3x3 cm and infested by Sarcoptes scabiei. All rabbits were adapted for 7 days so that parasites can grow and spreaded evenly across the surface of the skin. Every day, the rabbit skin affected by scabies was smeared twice with liniment tested at a dose of 25%. Macroscopic observation made on day 3, 5, 7 and microscopic observation made on the 3rd day after the treatment period for 7 days. All quantitative data is statistically tested using Analysis of Varians (ANOVA) with post hoc test methods Turkey and LSD method with 95% confidence level (a = 0.05). The results showed that in rabbits treated liniment coral kelimutu extract (P3) was revealed a better results than the group P0, P1 and P2. Based on statistical analysis post hoc testing methods Turkey and LSD method showed p = 0.000; R squared = 0.88 and of F (7,11) > F table (1.74), there fore it is concluded that there are significant differences between the groups P3 with P0, P1 and P2 to the attachment of wound closure, reduction of scab and the rising number of Sarcoptes scabiei death. Coral kelimutu extract is the most effective healing therapy used for scabies in rabbits. Keywords: liniment, coral kelimutu extract, lamtoro leaf extract, scabies

Item Type:	Other
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Vetenary Medicine > Vetenary Education Study Program
Depositing User:	Sulimin BP3
Date Deposited:	11 Oct 2022 07:29
Last Modified:	11 Oct 2022 07:29
URI:	http://erepository.uwks.ac.id/id/eprint/12934

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