Pemberian Ekstrak Buah Pare dan Diet Tinggi Lemak pada Penurunan Berat Badan Tikus Putih Jantan.

Harsa, I Made Subhawa (2019) Pemberian Ekstrak Buah Pare dan Diet Tinggi Lemak pada Penurunan Berat Badan Tikus Putih Jantan. Univ. Hang Tuah Surabaya. (Unpublished)

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Abstract

Abstract Background : Obesity is an energy balance disorder, ketogenic diet can reduce body weight. Bitter melon (Momordica charantia L.) is vegetable material that is often used as an antioxidant, hypocholesterolemia and hypotriglyceridemia drug. Cucurbitasin is a substance with a bitter taste on bitter melon (Momordica charantia L.) which causes decreasing appetite, resulting in a decrease in triglycerides. Bioactivity of bitter melon (Momordica charantia L.) can increase lipid oxidation, decreased accumulation of fat tissue which can reduce weight. Methodes : This research is using pre and post test randomized controlled group design with sample size 30 male white rats (Rattus norvegicus) divided into 3 groups, group 1 given standard feed, group 2 given high-fat diet with a dose of 2.5 ml and group 3 given a high-fat feed with dose of 2.5 ml and extract of bitter melon (Momordica charantia L.) at dose of 37.5 mg / 150 gBB by feeding tube every morning for 28 days. Data were analyzed by T-paired tests. Result : The T-paired test in each group found a significantly different result of p = 0,000. Conclution : given bitter melon (Momordica charantia L.) extract and high-fat diet can reduce weight male white rats (Rattus norvegicus). Keywords:Bitter molon extract, high fat feed, weight loss

Item Type:	Other
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine > Medicine Study Program
Depositing User:	Sulimin BP3
Date Deposited:	29 Dec 2020 05:22
Last Modified:	29 Dec 2020 05:22
URI:	http://erepository.uwks.ac.id/id/eprint/7608

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