Pola Prevalensi Escherichia coli Penghasil Extended Spectrum Beta-Lactamase (ESBL) Pada Flora Usus Ikan Bandeng Di Pasar Tradisional

Salsabillah, Dinara Safina (2025) Pola Prevalensi Escherichia coli Penghasil Extended Spectrum Beta-Lactamase (ESBL) Pada Flora Usus Ikan Bandeng Di Pasar Tradisional. [Tugas Akhir/Skripsi] (Unpublished)

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Abstract

Salsabillah, Dinara Safina. 2025. Pola Prevalensi Escherichia coli Penghasil Extended Spectrum Beta-Lactamase (ESBL) Pada Flora Usus Ikan Bandeng Di Pasar Tradisional Surabaya. Skripsi, Program Studi Pendidikan Dokter, Fakultas Kedokteran, Universitas Wijaya Kusuma Surabaya. Pembimbing: Kuntaman1, Masfufatun2. Escherichia coli termasuk dalam salah satu bakteri gram negative yang menghasilkan enzim Extended Spectrum Beta-Lactamase (ESBL) dan memiliki peran resistensi terhadap golongan beta-lactam. Adanya bakteri E.coli yang menghasilkan ESBL pada bahan pangan terutama pada ikan seperti ikan bandeng (Chanos chanos) menimbulkan potensi sumber penyebaran resistensi antimikroba (AMR) di manusia. Pada penelitian ini yang bertujuan untuk mengetahui pola prevalensi E.coli penghasil ESBL pada flora usus ikan bandeng yang dijual di pasar tradisional Kota Surabaya. Penelitian ini menggunakan metode deskriptif observasional dengan pendekatan cross sectional. Terdapat 50 sampel usus ikan bandeng yang di ambil dari beberapa kios di pasar tradisonal secara acak. Identifikasi bakteri E.coli dengan dilakukan penanaman di media MacConkey dengan cefotaxime 4 µL/ml dilanjutkan dengan uji Double Disk Synergy Test (DDST). Dari 50 sampel usus ikan bandeng yang di gunakan terdapat 34 68%) sampel yang menunjukkan hasil positif E.coli penghasil ESBL. Tingginya prevalensi dapat mengindikasikan bahwa potensi penyebaran reistensi antimikroba melalui rantai makanan, penanganan higinitas pangan dan mengontrol penggunaan antibiotic dalam pembudidayaan ikan perlu menjadi perhatian yang serius. Kata kunci: Escherichia coli, ESBL, Ikan bandeng, Resistensi antibiotic, Pasar tradisional, Surabaya. Salsabillah, Dinara Safina. 2025. Prevalence Pattern of Escherichia coli Producing Extended Spectrum Beta-Lactamase (ESBL) in the Intestinal Flora of Milkfish in Traditional Markets in Surabaya. Thesis, Medical Education Study Program, Faculty of Medicine, Wijaya Kusuma University, Surabaya. Advisor: Kuntaman1, Masfufatun2. Escherichia coli is one of the gram-negative bacteria that produces the Extended Spectrum Beta-Lactamase (ESBL) enzyme and has a role in resistance to the beta-lactam group. The presence of E. coli bacteria that produce ESBL in food, especially in fish such as milkfish (Chanos chanos) poses a potential source of the spread of antimicrobial resistance (AMR) in humans. This study aims to determine the prevalence of ESBL-producing E. coli in the intestinal flora of milkfish sold in traditional markets in Surabaya City. This study used a descriptive observational method with a cross-sectional approach. There were 50 samples of milkfish intestines taken from several stalls in traditional markets randomly. Identification of E. coli bacteria by planting in MacConkey media with 4 µL/ml cefotaxime followed by the Double Disk Synergy Test (DDST). Of the 50 milkfish intestine samples used, 34 (68%) samples showed positive results for ESBL-producing E. coli. The high prevalence may indicate that the potential for the spread of antimicrobial resistance through the food chain, food hygiene management and controlling the use of antibiotics in fish farming need serious attention. Keywords: Escherichia coli, ESBL, Milkfish, Antibiotic resistance, Traditional market, Surabaya

Item Type: Tugas Akhir/Skripsi
Uncontrolled Keywords: Kata kunci: Escherichia coli, ESBL, Ikan bandeng, Resistensi antibiotic, Pasar tradisional, Surabaya.
Subjects: R Medicine > RZ Other systems of medicine
Divisions: Faculty of Medicine > Medicine Study Program
Depositing User: Dinara Safina Salsabillah UWKS
Date Deposited: 28 Apr 2026 03:58
Last Modified: 28 Apr 2026 03:58
URI: http://erepository.uwks.ac.id/id/eprint/22153

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