Deteksi Penyebab Retardasi Mental pada Keluarga Penyandang Retardasi Mental di Desa Padangan Kediri

WULANDARI, RETNO DWI (2018) Deteksi Penyebab Retardasi Mental pada Keluarga Penyandang Retardasi Mental di Desa Padangan Kediri. Universitas Hang Tuah. (Unpublished)

Text 4. COVER DAN NASKAH.pdf Download (1MB)

Abstract

Abstract Background: Many family member were found with mental retardation in Padangan village, Kediri. Previous research showed students with trisomy 21, triple X syndrome dan suspect Fragile X syndrome in SLB Pelita Hati, Padangan Village, Kediri. Aims: To determine chromosomal abnormality and mutation in CGG repeat FMR1 gene in family with history mental retardation Methods: Cytogenetics analysis and PCR analysis to see mutation in CGG repeat FMR1 gene Results: From 12 samples, were found 2 pericentric inversion in Chromosome 9 and 1 Trisomy 21. Conclusion: Chromosomal abnormality was encountered in one student. Structural abnormality were seen in one student and his father. No mutation was found in FMR1 gene caused Fragile X syndrome in students and families. Keywords: Mental retardation, Cytogenetics, Molecular Analysis

Item Type:	Other
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine > Medicine Study Program
Depositing User:	Sulimin BP3
Date Deposited:	06 Sep 2023 09:53
Last Modified:	06 Sep 2023 09:53
URI:	http://erepository.uwks.ac.id/id/eprint/15364

Actions (login required)

View Item

Downloads